If your B12 is really low, it might take a few more days before the tiredness fades away
To keep your glutathione production at healthy levels, its best to avoid alcohol and manage your stress levels, since high cortisol levels deplete glutathione
Its also likely that the dose needed could be even lower (or even zero) in long-time (months) keto-adapted athletes since ketones can offset the need to maintain a higher blood glucose, and longer keto adaptation periods make the body better at ration carb fuel, supplied in small exogenous doses or generated by the body itself
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However, if your research protocol explicitly calls for an IM injection, your needle requirements change completely